Health Benefits of GLM
Green Lipped Mussel (GLM) contains different types of Omega 3 fatty acids: EPA, DHA, ETA and OTA.
All of them are necessary to the human body for optimal functioning and health. GLM extract is also rich in proteins, minerals and mucopolysaccharides. All of these nutrients are becoming more recognized for their effect on joint pain and swelling, cartilage production and general overall health.
GLM is an inflammation inhibitor in the body. When inflammation is prolonged or painful, damage to the tissues can occur, especially to joints and cartilage. Studies show that certain conditions such as asthma, arthritis, psoriasis and Crohn’s disease are alleviated to some extent by GLM (Green Lipped Mussel).
Docosahexaenoic acid (DHA:22:6 n-3) 19% and eicosapentaenoic acid (EPA; 20:5 n-3) 15% and palmitic acid (16:0) 15%, are the three major fatty acids of the Green Lipped Mussel.
Cholesterol is 31% of total sterols, others include occelasterol, nordehydrocholesterol, dehydrocholesterol, methylenecholesterol, brassicasterol, and desmosterol, all major sterols.
Lyprinol ( stabilised lipid extract of New Zealand green lipped mussel ): a potential preventative treatment modality for inflammatory bowel disease. J Gastroenterol. 2005 Apr;40(4):361-5. Tenikoff D, Murphy KJ, Le M, Howe PR, Howarth GS.Child Health Research Institute, Women’s and Children’s Hospital, North Adelaide, South Australia, Australia. Lyprinol (Pharmalink International), the stabilised lipid extract of the New Zealand green-lipped mussel, is currently used to relieve symptoms of arthritis.
We investigated the effect of pretreatment with lipid extract of the New Zealand green lipped mussel on experimentally induced inflammatory bowel disease (IBD) in mice. METHODS: Male C57BL/6 mice (aged 6 weeks) were gavaged daily for 13 days with (150 microl) olive oil (OO; n = 7), fish oil (FO; n = 8), or LYP (n = 8). Mice consumed 2% dextran sulfate sodium (DSS) for 6 days, starting on day 7. Body weight and disease activity index (DAI) scores were recorded daily. Colonic damage was determined by histopathology. Colonic inflammation was quantified by myeloperoxidase (MPO) activity.
RESULTS: lipid extract of the New Zealand green-lipped mussel treatment significantly reduced body weight loss, DAI scores, crypt area losses, and cecum and colon weights, compared with FO treatment. MPO activity was not significantly affected by any treatment.
CONCLUSIONS: These findings provide preliminary evidence that lipid extract of the New Zealand Mussels may be potentially useful in ameliorating symptoms of IBD. The benefit, however, is unlikely to be due to the omega-3 fatty acid content. Dose-response evaluation of lipid extract of the New Zealand green-lipped mussel in experimental IBD is warranted.
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